Interfacing Glycoscience With Disease And Clinical Practice
Hosted by: The Alliance of Glycobiologists for Detection of Cancer and Cancer Risk
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Co-sponsors: National Cancer Institute, National Institute of Allergy and Infectious Diseases, National Institute of General Medical Sciences, National Heart, Lung, and Blood Institute
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National Institutes of Health
Bethesda, MD 20892
|8:30 - 8:45 AM||Welcome
Sudhir Srivastava, PhD, MPH, NCI
|8:45 - 9:00 AM||NCI Glycomics Alliance: The First Five Years
Karl Krueger, PhD, NCI
|9:00 - 9:40 AM||
From Glycomimetic Compounds to Novel Drugs
John Magnani, PhD, Glycomimetics Inc.
|9:40 - 10:10 AM||The Status of Immunotoxin Trials Targeting Siglec-2 (CD22).
Ira Pastan, MD, National Cancer Institute, National Institutes of Health
|10:10 - 10:30 AM||Break|
|10:30 - 11:10 AM||Glycosyltransferase-Programmed Stereosubstitution (GPS): Sweetening the Applicability of Cellular Therapeutics
Robert Sackstein, MD, PhD, Harvard Medical School
|11:10 - 11:50 PM||The Roles of Surface Displayed Glycans in Viral Entry: From Structure to Function and Inhibition.
Carole Bewley, PhD, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health
|11:50 - 1:00 PM||Lunch|
|1:00 - 1:40 PM||Glycan Recognition at the Axon-myelin Interface: Implications for Axon Stability and Regeneration.
Ronald Schnaar, PhD, Johns Hopkins University
|1:40 - 2:20 PM||Regulation of Notch Signaling with Glycosylation
Robert Haltiwanger, PhD, SUNY Stony Brook
|2:20 - 2:40 PM||Break|
|2:40 - 3:20 PM||The Tn and SialylTn Antigens in Human Cancers: Prospects for Diagnosis, Treatment and Biological Pathways
Richard Cummings, PhD, Emory University
|3:20 - 4:00 PM||Oncogenesis Alters Glycan Expression that Directs Identification of Cancer-Specific Markers.
J. Michael Pierce, PhD, University of Georgia
|4:00 - 4:30 PM||Update on NRC Glycoscience Study
Chair: David Walt, PhD, Tufts University