Alliance of Glycobiologists

This image describes the structure of the Alliance. Arrows show the back and forth nature of the collaborative relationship among the laboratories, NIH Institutes, and the Alliance Coordination Unit.

Partners

CFG Nature - Functional Glycomics Gateway
National Center for Research Resources
Early Detection Research Network (EDRN)

Welcome

Welcome to the website for the Alliance of Glycobiologists for Detection of Cancer and Cancer Risk, a consortium of seven Tumor Glycomics Laboratories and research partners. The Alliance is working to reveal the cancer-related dynamics of complex carbohydrates, and to develop new validated, clinical biomarkers for early cancer detection and risk assessment.

By combining resources and expertise, the Alliance brings an unrivaled strength to this emerging field. Here you will find publications, recent news and media coverage, upcoming meetings and events, contact information and scientific resources from Alliance members.

Mission

The mission of the Alliance is to study structure and function of glycans in relation to cancer development towards developing clinically useful biomarkers for the early detection of cancer by using a variety of approaches and technologies. This charge also requires extensive collaborations across institutions with different skills and facilities to accelerate glycan-based biomarkers to the forefront of NCI's efforts to detect and diagnose cancer at early stages.

The unique needs of the laboratories for technologies embracing carbohydrate chemistry are further supported by the Consortium for Functional Glycomics (CFG) through the National Institute of General Medical Sciences (NIGMS), and the Glycomics and Glycotechnology Resource Centers through the National Center for Research Resources (NCRR). The Alliance will closely work with the NCI's Early Detection Research Network (EDRN) to validate promising glycans for clinical use.

A Coordination Unit (CU) representing seven Tumor Glycomics Laboratories, CFG and EDRN, and program staff from NCI, NIGMS and NCRR integrates the activities of the Alliance.

 

In Focus

Mining the O-glycoproteome using zinc-finger nuclease-glycoengineered SimpleCell lines. Nat Methods. 2011; 8:977-82


The National Academy of Sciences/National Research Council is conducting a study entitled ?Assessing the Importance and Impact of Glycomics and Glycosciences.? For more information on this study see: http://glyco.nas.edu/

The scientific community is being asked to provide feedback to the NRC on this study at http://glyco.nas.edu/feedback

Phase I background report on glycosciences and glycomics in the US.


More news

Last updated: May 10,  2012
 
U.S. Department of Health & Human Services National Institutes of Health USA.gov